Targeting hematologic malignancies with oncolytic vaccinia virus constructs

نویسندگان

  • Nanhai Chen
  • Mehmet Kilinc
  • Qian Zhang
  • Jason Aguilar
  • Desislava Tsoneva
  • Maysam Pessian
  • Boris Minev
  • Aladar Szalay
چکیده

Background Oncolytic viruses are a promising approach for cancer therapy. Recent clinical trials proved the safety and antitumor activity of several oncolytic viruses in solid tumors. However, very little is known about the potential of the oncolytic viruses to target hematologic malignancies. Careful analysis of the effects of the oncolytic viruses in patients with hematologic malignancies will lead to the development of more specific and effective treatment strategies.

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عنوان ژورنال:

دوره 1  شماره 

صفحات  -

تاریخ انتشار 2013